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Other Products
Ferring Pharmaceuticals Inc. products closely resemble those found naturally
in the body to minimize undesirable side-effects, and to help achieve
desired results with low doses. Traditionally, Ferring has concentrated
its research on modifying posterior pituitary hormones to develop new
peptide-based pharmaceuticals, but recent years have led to work with
other substances such as GnRH-analogues, enzyme inhibitors, and oxytocin
receptor blockers.
ACTHREL® (corticorelin ovine triflutate for injection)
Acthrel is the first stimulation diagnostic agent for the differential
diagnosis of Cushing's syndrome. It is indicated for differentiating pituitary
and ectopic production of ACTH in patients with ACTH-dependent Cushing's
syndrome. Acthrel, administered in a single IV dose in the physician's
office or lab, provides new levels of sensitivity, specificity, and convenience
to meet the diagnostic challenges of this category.
Please note:
Adverse effects reported with 1 mcg/kg or 100 mcg/patient include flushing of the face,
neck, and upper chest (16%; 45/276), beginning almost immediately and lasting 3 to 5 minutes.
Recipients have also reported an urge to take a deep breath (6%; 3/49), which occurs with a
timing similar to, but less frequently than, that of flushing.
Please click here to see the side effects, contraindications, and other full prescribing information.
DESMOPRESSIN ACETATE
Desmopressin acetate, a vasopressin analog discovered by The Ferring Group,
stimulates the kidneys to conserve water and concentrate urine, leading
to an initial approval in the United States for the treatment of diabetes
insipidus. Later clinical studies found desmopressin acetate effective
for bedwetting, and the drug was cleared for the treatment of primary
nocturnal enuresis in the late 1980s. Ferring Pharmaceuticals now markets
the rhinal product and injectables.
Please note (rhinal tube):
Infrequently, high dosages of intranasal desmopressin acetate have produced transient headache
and nausea. Nasal congestion, rhinitis and flushing have also been reported occasionally along
with mild abdominal cramps. These symptoms disappeared with reduction in dosage. Nosebleed, sore
throat, cough and upper respiratory infections have also been reported.
Please click here to see the side effects, contraindications, and other full prescribing information. (rhinal tube)
Please note (injection):
Infrequently, desmopressin acetate has produced transient headache, nausea, mild abdominal
cramps and vulval pain. These symptoms disappeared with reduction in dosage. Occasionally,
injection of desmopressin acetate has produced local erythema, swelling or burning pain.
Occasional facial flushing has been reported with the administration of desmopressin acetate.
Desmopressin acetate injection has infrequently produced changes in blood pressure causing
either a slight elevation or a transient fall and a compensatory increase in heart rate. Severe
allergic reactions including anaphylaxis have been reported rarely with desmopressin acetate
injection.
Please click here to see the side effects, contraindications, and other full prescribing information. (injection)
©2005 Ferring Pharmaceuticals
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